I got the same kind of issue and tried like everything...
On my side i'm stuck at the "Follow Panam" part right after the interaction with Saul. Panam somehow teleported back near the tank and don't want to move. Stuck with 3 blue dialog optionswhen talking directly to her.
I've spent more than 1 hour trying to catch what's wrong and testing like everything; even running with a car on Panam...
What I can tell is that it's not only related to Panam but also Saul and there may be a relation with another totally different quest about Brendan (see bellow).
Video: Cyberpunk 2077 - Queen of the Highway bug - YouTube
Saul is COMPLETELY bugued. At 1.30 you can see I get a phone call from Judy and you can see Saul on the miniature of the call above Judy. It happen with half of the calls i'm receiving now. Saul is like a plant not moving and you cannot interract with him anymore. (see him at 2.50 of my video)
When I get close to Panam's/Saul's supposed location (where the "Follow Panam" should start) and I try to call panam on phone, I get :
- Saul's minitaure....
- Dialog option is related to "Brandan" that is a totally different (and funny) quest !
Brendan | Cyberpunk Wiki | Fandom
- A double dialog option (tried all of them) and after one of the choices I can see her getting up but it does not change anything.
Hope this can help solving the issue for a fix...