Yes and no, I think it depends on a lot of things. Especially the expansions and the direction they will taking.
One of the massive issues is that V is pretty much dead as it is now. Even if some of the expansions make you continue trying to find a cure, you still have a lot of endings which might be difficult to bring into something meaningful for all of them, especially the suicide one.
Also because they somehow need to respect whatever choice the players made.
And im not sure how exciting an expansion will be playing V in a earlier stage of her/his life knowing that you will eventually die anyway, it sort of remove all tension from the game and also makes it kind of weird, because we know V is going to survive at least to the end of the original game. So the game would be sort of like the Star wars Solo movie, they can't really build any tensions in regard to putting the player in life or dead situations, because we know that V is not going to die anyway.
Alternatively, they have to introduce a new character or let you play one of the others more established one. But not only is it rough introducing a new character in an expansion and make people care, but also its sort of weird playing one of the established one.
Also I don't think an expansion following the original design is going to do all that well to be honest. Because I think a lot of people realized towards the end of CP, that there are some serious flaws in the game mechanics, especially with the combat system and the economy etc.
Furthermore, if the expansion also doesn't hold a lot of branching options, they are going to get heat from that as well big time, because despite what some people claim, it was one of their biggest promises with CP, and it simply didn't deliver here. They also have the whole lifepath that is extremely poorly integrated into the game.
Then they could make it so you play Silverhand, but honestly, I don't think this character is loved enough for people to care playing him and he is to well established for it anyway. Meaning it would be silly to give him gorilla arms etc.
They have said that these bigger expansions are going to work sort of like they did in TW3, but the huge difference is, that Geralt weren't killed in the original game, they had a fairly good combat system and underlaying systems in general in the TW3 universe, so they simply had to create a new and interesting story based on what they already had. And lets be honest, they manage it and did a very good job at that. But im not convinced that it will go that easy with CP, because the foundation is not even close to being as solid as that of TW3.
I think their best chance is to rework CP, to make it more of an open world / sandbox experience than it currently is, because at the moment, I don't think there is a whole lot of replayability in the game, except as a shooter game, which can be fun, but the story is not exciting the second time in my opinion at least. And even if they made it more of a sandbox game, im not sure it will work to well either, due to how the story plays out. I mean V is pretty much a wasted character now as I see it.
At least, with the current knowledge of CP, im not convinced that these expansions are going to be all that good to be honest. It much easier at least to see how expansions for TW3 had the potential to be massive successes.
Im pretty sure that was faked. At least based on the Bloomberg article with interviews from developers, most of the stuff in that 48 minute video were created solely for that video alone, at least from how I understood it. Again, I think what they showed was their ambition rather than the actual game, and they wanted to see peoples reaction to it, to see if they should go for something like that.
I could imagine that this have a lot to do with the potential lawsuits going on and because there are so many bugs and missing features in the game that its way to early to even talk about expansions.