That is enough about whether or not Keanu Reeves's involvement affected the game or how much. Back on topic.
Understood.
I'd rather discuss the potentials of the future anyway. The past is done and gone. That said.....
Looking at the potentials for proper expansion content, a full-on Biotechnica clone expansion could really work well for continuing the story. Something like this perhaps:
When you consider that V is going to die regardless of ending, they could pick up a continuing narrative from one of two points: the Embers point of no return, or a point 6 months later. The Embers point would be easiest. The later point would need a bit more "creativity" to make work. Depending on the ending the player went through, a short (2 minute maybe?) montage' video depicting what the player may have been doing since (in first person perspective for obvious reasons). This would obviously need to vary from player to player relative to their ending, but wouldn't need to exceed the total number of endings.
If the player committed suicide, the montage' would need to be a bit more special. Perhaps involving one of the other main characters. Judy, PanAm, River, Kerry, etc., in a voiceover explaining how they arrived at this point.
Fade in to the player awakening in a Biotechnica clinic or lab of some sort, with Viktor standing over them as they awaken to provide a neutral, friendly face as the player awakens. A construct in their own cloned body (the "neurologically indifferent vessel" Hellman spoke of). And a natural fit for a replica of the relic (designed and built at Biotechnica by Hellman maybe?). This also affords the player an opportunity to make changes/adjustments to their current look using a mirror in said lab/clinic. "Nice work....." but this or that is "just a little off" or "I would never have my hair cut this way!" Or if the player likes their pre-expansion look, they could just exit without changing a thing.
Well, there's a start. Things could go in any direction from there