Well, now we'll have the mutagens for the permanent boosts only set while meditating. I don't remember how they could be created, but if they require a lot of ingredients, including some really rare ones, that could balance things a bit.
We'll have the general use on the fly potions, that depending on the type could require more or less ingredients to create, and now that we can experiment with the ingredients, it could add more variety there. The use of rare ingredients would also be nice.
I really want to see it in game, because just hording ingredients is not exactly fun. In the W2 I ended up so many ingredients that I sold a lot of them and still had a ton of potions, but still I only had 5 or 6 that I really used.
After a while I stared experimenting with different combinations of potions, but it was just for the sake of trying out something else, I really hope the potions this time around provide more flexibility and have some real effect, even if in combination with some other potions, and not be limited to only a handful of really useful ones.
At this point I can safely say that I can live with the current system. There are still things that we don't know, and who knows, after trying it for our selves it could turn out to be really good.
Now I'm very interested in the skill system.