Found a setting that gives me 60fps everywhere except Novigrad (that still drops to 45 on average due to CPU hammering) while keeping RT enabled and with perfect framepacing to boot, yay. And it looks great on my 1080p plasma.
Spec: 5800X3D, RTX 3080Ti both default
First, disable vsync and frame limit in-game and enable it in nvidia control panel, also enable 60fps limit there.
Then, start game, in the menu disable hairworks and RT shadows (they flicker and pop-in), leave RTGI, RTAO and RT Reflections enabled. Resolution 1440p, DLSS performance.
Detail settings:
With this setting, the game is 100% smooth and well frame paced everywhere except Novigrad, at least from what I tested.
And I love how it looks.