Only three things bug me to varying extend:
(not in any particular order)
1. Third person (on the low end though, if I could see my character more and at will, cool to have)
2. Lack of apartment progression or rather being able to get / use different ones
3. Changed main narrative compared to early on expectations
Brief elaborations:
Third person - Well, already covered. Not that of a huge deal for me, but would gladly take it.
Apartments - well, only disappointed because initially it was stated or implied heavily that V could use different ones. While I don't expect an apartment or interior simulator or "The Cyberpunk Sims", it would add to a progression you can feel or simply catering to your character if you were able to also have lower end or higher end apartments in city areas you like.
Changed main narrative - Initially, years ago, many things about the game were naturally unclear. There were perhaps mostly unclear info snippets, expectations and assumptions floating about. But I vaguely recall something along the lines of opting to cover the various CP2020 "classes" ingame.
Long story short to get to the chase, I assumed and personally hoped, as I am a fan of this, to be able to have a character that was able to join different factions or be tied to them depending on "class", if they would've added 'classes'. I am a fan of "belonging" to some group or faction, to join them, and had hoped to play a cop or corpo. You can imagine my disappointment when it became clear this was not the case.
Now, don't get me wrong. I'm not saying this is bad. They went for another design route to have V as some kind of unspecified Merc (not counting their backgrounds I mean) who never gets tied to factions the hard way. It might be easier for them, the game surely won't automatically be bad because I cant have it my original way, but I won't pretend I'm as happy about it than I would've been with "classic factions" - even if it meant more branching out because you had to cover different factions and their unique content.
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The last aspect is prolly the biggest impact for me - with that, the game might've been truly or near-perfect form in terms of getting what I was hoping to get before. This is why I heavily advertise for modding and a certain cop related content thread, however, as this is plan B for either this game via mods or DLC, or the follow-up games.
I feel it can cater to people possibly more IF done 'right' (I know, subjective), but nevertheless I look forward to this game.