Memes asside. I believe smoke, drugs and alcohol go hand to hand with the cyberpunk genere. Low life, high tech. Human life does not matter. Also you roleplay an edgerunner, a bouty hunter that is almost certain to die from a bullet any time soon, so you experience all you can because most edgerunners don't live too long, and all of them smoke and drink.
Just this small consideration, otherwise keep the memes coming guys, as I said before: this post is a pure meme goldmine.
PS: go watch Cowboy Bebop.