Did two things, not sure which fixed it or if both needed, but my situation was edge case. In case here's what I did.
Ensure that your RTX card is selected in Physx settings.
Nvidia Control Panel -> Configure Surround, Physx
I use an egpu, so my laptop has a 1080 and an integrated GPU. I disabled the other Nvidia card in case DLSS setting will not enable because it thinks I may switch to the 1080.
Not sure if one or both were needed but DLSS is now enabled in game.