I just started B&W, and have only done the main quest up to and completing "The Beast of Toussaint". I have not gone back to the estate yet after the duchess gifted it to me.
The only non-Main quest I've completed thus far is the "Turn and Face The Strange" quest (I got the new section of the character screen).
Should I wait now, for either a patch or after doing something else before returning to Corvo Bianco and starting, "No Place Like Home"?
You can start the quest "No place like home", but i high recomend when you make the upgrades in corvo bianco use the meditation to pass time and see if the upgrades are OK.
Don't make the same mistake that us made... Most here made the mistake of leaving tousain and corvo bianco upgrades buged.
Look this topic for more INFO