Just thought about something.
Since this game will introduce the Cyberpunk universe to a lot of people, I figure you'll have to hang around in every part of the universe (corporate, night city, gangs, combat zone, etc...), so people can discover and understand the world by themselves.
I doubt they'll go on a "one storyline only" route, they kind of said that they wanted to move on from the witcher, and do something "new".
There will probably have "one focal point", a global event, the thing why you're here, etc... And you'll do your way around it, more than following a single track from the begining to the end.
It's still to see how they'll manage it tho, but it would be cool to see the place you'll go interacting in different way depending on your actions, etc...
Not in a GTA mindset you know "wait 5mn and all your stars are gone", but something really deep inside game itself.
Like, in real life, if you kill someone, shoot down a full police squad and make a whole rampage in the street, they won't be "Oh well, he walked away for 10mn, I bet we'll never see him again", here you should have the pressure you know?
Like "ok, I need to put this guy down, but if I get caught, my game is fucked up for this place", so depending on what you did, who you helped (or who you didn't helped either or whatever), the place should change, like a gang taking over another one (you'd see fresh graffitis over old one, and more guys from one gang in a location), people would be nice to you or avoid you, even shooting at you.
You could be in touch with the police, or having to avoid them at all cost.
Since there would be plenty of side quest, each one would change the world, but depending on what you did, in which order, ect... it could change the world in different order, creating different events resulting of it (like, if you release a chemical agent in one mission, and that you blowed up the anti-chemical factory in a previous one, you'd have acid rain, media talking on it, etc...).
Also, depending on your rep, you'd have media or not on your back
Like, if you're very sneaky and quiet, media will never heard of you, you'll be like a ghost.
Now, if you like to play it with attitude, like a "punk", of course, you'll have your reputation, and you'll have a bunch of media guys, following you like a bunch of monkeys to get a scoop on your actions.
Try sneaking in a building with a dude and a camera behind you haha.
Everyone expect "huge" things when it's about having the world reacting to you, but those small little things would make the game even more "alive", and create totaly crazy situations (it's already crazy to have a whole media crew sticking on your back, now take it to a whole new level a get a another media team shooting each other to get a scoop about you).
Same, if you're a cop and act good, people will probably be nice with you (but not gangs), and vice versa.
If you screwed and killed someone everybody love, you're screwed.
Media could be fun too, nowadays, media are all "money money money" with audience and all of this, so you could have something related to it, and depending on the audience you make. If you're a kind of paparazzi, or something like this, doing "audience friendly" things trying to know what kind of guy the last braindance's star loves to date, or doing cool reportage over "how corporate plazza is a beautifull place", people will probably love it, on the other hand, if you're an hardcore journalist, you'll end in a crappy pirate TV station, telling the thruth that no one want to hear, ect...
People would react differently depending on what channel you're on (I'm more a N54 guy, Never heard of your tv program, etc...)
Even there, you could make a lot of thing with the audimat stuff, like trying to do "audience friendly" stuff on your pirate channel, and wow, it works, now N54 is coming to get you on their channel, you say yes, and 2 days later your old Pirate Channel has mysteriously been burned down, and people calls you "sell off", etc...
A netrunner could have stalkers on the web and in real life, etc...
There are plenty ways to make the world reacting to you on a lot of scales that I hope they'll have fun with it and gives us something crazy.