I love these scripted action-movie-like events, but it's QTE or never. The uncharted series and GOW 2018 do it quite well, but it's still QTE and not in FPP.I imagine a fight like this:
I'm sitting at the backseat with some strangers and the situation gets heating up. They(or she/he) aim at me with a pistol and it becomes a hand-to-hand fight in the car. It may sound awkward, but I'm sure that guys at CDPR can make it in the right way.
Also, it'd be interesting to fight in the subway with some thugs being surrounded by lots of innocent people.