My first and hence more personal playthrough would be none other than the Media (if they even include it). As I said before, these archetypes whose actions aren't so based in violence are so exotic in an RPG or in a videogame.
You know, when I put myself to read Transmetropolitan the first couple of episodes rubbed me the wrong way. I didn't think Medias would play such a role in a cyberpunk setting. I thought they would be what else but puppets of corrupt governments and corporations, always censoring and filtering the more critical messages (I live in a country where there doesn't seem to exist such a thing as "facts", take as an example how media reflects the following of a protest and the numbers don't add up). But then I just loosened up a bit and said to myself: this is a cyberpunk setting where journalims "IS a thing". So maybe the Word (the newspaper on which Spider Jerusalem wrote his columns) with its ubiquitous presence and not that apathetic readers is a little "fantastic", maybe you can rework it as being somewhat of a blogger or a Julian Assange.
So, yeah, I want to roll a Media character and call him Israel Escorpio. And I want to be able to wield a handcam like it was a firearm and have it record as a mechanic (not necesarilly have real video but, I don't know, gain believability, generate "evidence" as a quest item or whatever), or have my cybereyes and cyberears record.
The next one maybe a Rockerboy, the next more exotic.