In my opinion a complex inventory goes hand in hand with a complex RPG, so this side effect is inevitable (besides, I didn't feel bad about it yet).
I just played some first hours.
The tutorial was nice, I first tried to use the keyboard as I did in the witcher 2, but they changed some keys what confused me a lot, so I decided to try out the gamepad and after some time I got quite used to it.
I have to play on the lowest possible graphic settings, but even now it already looks quite nice. Sadly my pc crashes whenever I try to dive into the water, but well, that's just my pc's fault^^ In 2 days I'll have a new notebook (was about time) and can hopefully play it on high graphic settings then - looking forward to it.
The prologue in white orchard is already huge. I spent already like 5 hours, running around, exploring all the spots marked on the minimap.
I am playing on the highest difficulty level. I also played the witcher 2 on dark mode, but I have to say, I died like 100 times already, to simple creatures such as drowners or ghouls, not to mention wraiths... but no problem, I'll handle it^^ The only thing I don't like about this difficulty level is that I don't regenerate automatically... This simply means I have to eat and drink all the time which is a bit annoying.
The character system seems really slow to me, I don't know how many hours it takes until I can finally use the alternative igni sign^^
But whatever - If this prologue is already so huge, I don't doubt I'm gonna spend years exploring the skellige isles and the mainland around novigrad and oxenfurt!

I hope everyone just enjoys as much as I do^^