V comes into the game with 3 different background stories. So it would be easy to also split up the story going forward? One new game/major expansion could be Johnny with a new start in a new town. The V endings can be merged quite easily with an initial split story line similar to the current game.
All Vs have 6 months to live, all have the same problem of an incompatible body. Same people/partners left and stayed in town regardless of the ending. In the judgement endings Arasaka is in shambles. To align this with the Joker ending, it wont be that hard to ram a subway tunnel drill into Saka tower to steal some tech you need to live and along the way bring down Arasaka? So all V endings could easily be merged at one ripper, who promises they's be able to solve the problem with the incompatibility, … and then you go and try solve it.
The endings were quite forcefully aligned at times. I am thinking for instance of Judy in the Hanoku ending. You get the message she’s gonna leave town on the way down to earth… clearly she could have waited 6 months with the new start? It seems that they aligned all endings to some planned story line, but often did not have the time to make it work properly (get people out of town, get Johnny and V into different story lines, 6 month to live, etc. )
Personally I think, V has a will to fight for their life through hell and back, and its been teased that there could be a solution to the incompatible body. So I found it weird if she’d now just put her feet up and dies? Also, it is such a cliff hanger.
Generally, I’d say they made sure to have all cards in the end to continue the story in whatever shape they want it. They also created a really fun universe with Cyberpunk and I am sure they will try to leverage it: there could be DLCs with parallel story lines, with different characters, the 3 prequels (Corpo, Nomad, Street Kid) could be exploited…
Given a long break I guess they will be working on something bigger to bring people back into the game and then follow up with smaller DLCs to keep people going? Waht we are going to see depends on, can they fix their issues, and will people buy.