I think it could be possible that a couple more stories could be done. I like to consider this series the "Street Kid" lifepath, so maybe a story of someone rising up the corpo ladder and another one about a nomad crew. And tragedy being the core of Cyberpunk definitely is refreshing to the happy endings that dominate mainstream media. Course, doesn't have to be more death necessarily to be a tragedy (e.g. idealistic corpo kid turned to a merciless corpo exec a la Game of Thrones drama), but it should run the same themes of tragedy without repeating the first story.
Well, if you look things about the genre, it's in the game already, or say demonstration. I'm reposting but just think this as a show:
...take 6th Street Gang for example.
They are mostly war veterans. We learn via other missions that state doesn't give a damn about them and 6th Street, while wearing NUSA colors and that, like to appear principled but they are just another criminal organization and eliminate external and internal threats to their ghetto pharmacy etc. business. What makes this particularly interesting is that not only that kind of thing could happen in similar conditions, it empirically did in the Soviet Union with their veterans from the Soviet - Afghanistan war. They made Russian mafia became whole a lot a different level player that it was, sometimes hijacking entire existing gangs and turning them to their own business (who were ones to take advantage of their situation).
Game also gives as a scenario with private armies and rises a question about what about those who get fucked in those organizations. Who in the end pays the bill, because if it's not corp (which may conveniently fold to avoid long term liabilities) the bill for society still can happens if/when those vets take what they need, maybe failing, but bill might be still there in blood.
I think there's lots of audience for this game that doesn't talk. It's that if you are attracted by this kind of detail and appreciation for real world matters, it might be a difficult to connect with parts of audience who also appreciate story aspects but are to fan fiction and romances. It's not that the latter are bad things, it's that there just isn't much common ground to have a conversation.
While Cyberpunk the genre can be a specificly niche market, good animation, good world-building, and good story are not. Present a good story and people will end up watching regardless what type of world it is. Some people I know would've never watched Game of Thrones or Breaking Bad if it wasn't for the fact they were just generally good stories that were well acted. Give them something to relate to, think about, and learn from and I think a couple more stories could be told.
Good story... yeah. There's limited amount of people on this planet that can do that and frankly, the US haven't been on the map for ages for their size. It's not that they don't have able writers, it's a matter that they just don't appear to want them. It's weird, I don't know, so don't ask me.
If you look at the CP 2020 rulebook that comes with the game, you can see counter culture back of the days, dark humor and all that, like how some of people to cyberpunk in generation x dealed with things. Advancing in technology doesn't mean we become somehow better homo sapiens.
Edgerunners is never short selling intellectually, that something like tech makes us but better killers. That not only works in context of story, for cyberpunk that's essential, but for masses, it's something that makes sense. It's not the 80's anymore.
So, they did 6th. Street into game we got a less than two years ago. Like Mike Pondsmith said, future 5 minutes from now. Look what's happening in the world right now. Know that's over, doesn't mean everything is over. This is cyberpunk genre, once again, fiction today, to understand what lies ahead. We can at least prepare.
For topics like this, cover them in intellectual way, it reaches way more people than gaming audience.
Game, it might be the next GTA with blinking lights for cyberpsychosis, but other mediums, they can let their writers still shine and customers are going to be there.