Same here. I was 80h in with first playthrough, was enjoying the game, had 50-70fps (with occasional drops to 40fps in busy areas but it didn't bother me). After 1.05 patch I'm getting huge drops in areas that were fine before (for example I get 15fps in Afterlife and area outside). Tried to do a couple of missions but it's unplayable at this moment :/
Playing 1440p, mostly Medium (LOD - High), RT On, DLSS - Performance.
My PC:
AMD Ryzen 5 3600
RTX 2070 Super
16Gb 3600 ram
SSD
Win10
Would really appreciate a fix for this problem. I really do enjoy the game but at this moment I'm unable to finish the missions.