Interesting topic.
For myself, I thought Act One was my favorite. I agree that some of the characters in Act Two were good and I did like Panam...as a character in the story. She was determined, strong and certainly had personality and yet very annoying. Unlike many others, I did not romance her or anyone for that matter, I can do without the romance side. I liked River and his quest, and I really liked Jackie in Act One. Unlike many others, Judy was just another part of the story, I saw nothing special about her. Further I do not see why you (seem) to have to romance anyone to apparently determine an ending for the game. My opinion, but there you go.
But I thought this story (game) was about V, that was the given impression anyway. 'Make this world yours!' The way the game progressed, it was somebody's world, but not mine. As it turned out, it was Johnny Silverhands story and his world, that is where the game fell apart for me. Then there are the endings of the game, all of which are bad. Yes, before you jump on me, I understand that the 'Cyber Punk' world is dark, gloomy...what ever, but that still doesn't mean you can't have one good ending for V. At the risk of using a cliche, an ending that would allow V to ride off into the sunset on his / her bike and live happily ever after, or something like that. I'm fairly certain some would agree with this.
During Act 2, I was getting tired of the constant attacks V was having, and Johnny's banter. There was just too much of that going on and sometimes V would have one of those attacks while in a fight. I feel that Johnny Silverhands story should have been a seperate DLC on it's own, and not part of V's main story from Act 1. They (CDPR) should have carried this through with V (and Jackie) as the games main storyline.
Despite this, I still enjoy the game and am now on my second play through. Using what I learned on my first game and just take my time. I will not play Act Three again because of the endings, I'll just go as far as I can go.
This game has enormous potential and I think in time CDPR will get things sorted on all platforms.