I'll preface this by saying that I have no issues with Keanu Reeves. By all accounts, he's an angel.
But I've gotta say, I'm not a fan of them introducing such a big name into the game. It'd be one thing if it was just VO, but adding likeness as well? Completely immersion breaking, IMO. Last year, CDPR showed us that they can craft memorable, unique characters (Dum Dum, Dexter D., Stout, Jackie, Vic, etc.). Now when I come across Silverhand in the game, all I can see is Keanu Reeves.
My only hope at this point is that Silverhand plays a small role in the game.