I just upgraded from windows 7 to 10 version 10.0.17763 1809. GOG 1.31 was fine in 7, now I am having this same issue; BOTH my keyboard and mouse are not accessible in game. Works fine at the main menu and escape menu in game (alt tab brings it up) but not live in game. I reinstalled the game and it persisted. I have done another dist-upgrade and it persisted. Disabled defender & exploit protections, DEP & aslr + all the rest, disabled DMA protections, secureboot parameters and other protections under group policy... though I have no secure boot motherboard. I deleted the 3 settings files & 'xinput1_3.dll' file. Removed the only addon I had, a debugger. Reinstalled game after removing addons. Loaded game as admin... removed all saved material on fresh install, no luck there either. Created a batch file, loaded '"witcher.exe" -window' with admin mode, no luck. I do not use nvidia geforce experience, and do not install any driver nor nvidia PhysXbut the primary display driver, i repeat no driver but the primary display driver. I use only windows firewall and windows defender on demand scan. I removed all xbox windows 10 provisioned components via DISM.
I am quite amazed its been 3 years now and nobody has figured this one out. Its a game compatibility issue to be sure, possibly with windows drivers; eveyrthing was working fine in 7.
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SigilFey I looked inside of input.settings and there is only two lines, the line you suggest I add is wiped after loading the game. All assigned keyboard and mouse keys are wiped upon starting the game, resetting key layout to default does not work either, all keys are left empty.
Am using a microsoft natural ergonomic 4000 keybaord & Anker TM137U mouse. No extra HID mouse/keyboard software installed, just default drivers. Windowed & Fullscreen mode break the keybaord and mouse the same.
The game needs a patch