It would take a bit of setup, but if your *nix setup supports VBox with hardware passthrough, and your system can handle it, it's possible to play pretty much anything in *nix. A friend who refuses to dual-boot does this for all his games. Could be a solution until such time there's native support for it, if there ever is. Time consuming though, and you need a system capable of throwing a lot of resources at it without affecting the base OS. It's likely easier and faster just to dual-boot. Another person tried using WINE for both GOG and Gwent, and that works alright for them some of the time. I wouldn't want to try it after attempting WINE+Diablo 3.