"Application has been blocked from accessing Graphics hardware,"
This is typically a drivers issue or a faulty hardware issue.
Typically.
I know you already indicated having reinstalled your drivers but how did you reinstall them? I'm an Nvidia boy, so I have no idea if AMD offers something similar but Nvidia has a full reinstall option in it's software.
People use that thinking it really cleans their system from drivers before installing new ones but in my experience, it doesn't. Did you use something like that or did you use something like DDU to properly scrub your system from your graphics drivers And then reinstalled them?
If it's the former, please use DDU to clean your drivers and reinstall them.
If you've already used DDU to do it all, is your GPU working correctly? Are you monitoring it as you begin to play all the way to the inevitable crash?
If yes, what temperatures are we looking at here? Do you have any other game that is as demanding on your GPU to test it out on?
I have seen this error pop up because of something as simple as one of the GPU's fans not working.
Have you taken a look at your event logs in Windows around the time you crashed? Something like that is bound to have created critical errors which could give you some insight as to what is happening.