Carefully optimistic.
While Mass Effect Andromeda was a great game (actually it was in many ways better, especially storywise, than ME2 and of course ME3, and people should finally come around accepting that...), it was obviously an attempt to "plant" the MilkyWay races into a new setting/location, because Bioware wrote themselves into a stupid, unnecessary corner with the red/blue/green stupidity.
i just hope that - again unpopulat I suppose - we get 600 years into the future, play again as Femshep Reborn, Liara is the only recurring old char (and wouldn't even need her, but yeah, those fanboys of hers....), and we get a tie-up with Andormeda.
Because I want more Shepard, and I want definatly more Ryder.
Will Bioware deliver? Well ... at least around here nobody should mock that studio ever again by comparing them to the "superior" CD Red ... I have higher hopes Bioware/EA delivering a great ME5 that undoes the stupidity of ME3 than I have with CD Red rectifying their silly endings for CP2077 ...