I have the same problem. If you check the system RAM usage either via "task manager" or some 3rd party soft, you can see the RAM is filling up constantly, although the game uses only around 4gb. I have reported it as a bug as well, no idea if they look into it.
Im running Win7, where it is most visible. I have 16gb of ram in my system. The most noticeable and fastest time when RAM fills up is in your Apartment, sorting out inventory and moving items into/from stash. In this process the RAM usage skyrockets up in few minutes and fills the system RAM completely until freeze or crash.
The second visible time is when you drive fast through the city, not the outskirts but for example from Watson to pacifica.
As well every game LOAD fills up the RAM a bit - 200-400mb. I have noticed this issue with Loading on Windows 10 as well, but the other problems dont seem to fill the RAM that fast or almost none.
But I saw RAM usage jump up around 800mb just for completing a small quest with NIX without going out of the bar or doing anything different. This was as well on Win10.
I must restart the game every hour and watch out for the RAM usage so it dont crash in the middle of something.
It is really annoying and game experience breaking.