GFWL is pretty much a deal breaker for me. It was just a nightmare to deal with when I last tried it with FO3. The only DRM system I hated more was Origin with ME3. The game was bad enough, but having the action freeze almost every minute because Origin popped up a message saying I had lost my connection to their servers was not only immersion breaking on its own, but led to whole conversations being skipped, and that was during the single player. I never bothered with the multiplayer, but in that context it would have been catastrophic.
I had a similar, if no where near as bad time with GFWL. Shortly after FO3's release a user made hack that disabled GFWL was released, so it could be entirely ignored. Maybe they have improved, but I really don't feel like experimenting for what sounds like another sloppy port.