I'm not sure, I guess it depends on how much custom stuff they put in UE.
Mass Effect was UE3,Outer Worlds is UE4,Octopath Traveler is also UE4 and is quite different than Outer Worlds... for sure all game engines have their "signature" in it-Unity is much more characteristic in that regard-, but you can customize them quite a bit also.
That's what makes UE such a popular engine. It has worn an impressive number of widely different hats throughout it's many iterations.
It's a very powerful engine, extremely user friendly (seriously, fire it up once for shits and giggles - it is very user-friendly) and is very flexible. I have no doubt that it'll allow CDPR to create an incredibly game worthy of it's predecessors.