throw the round. He buffs 5 points and damages 1 point per turn. You got nothing to counter that. Play Bran and spy. Save Shackle for later. The chance is high that he play Neneke or Shani to revive dandelion. Or even keep him on board with resilience.
As above, bleed the opponent as much as possible while holding your gold cards in reserve for later rounds. Then hope you draw something useful to counter the usual NR medic/KOB/priscilla/etc combo.