Seeing all the issues here, I guess I can consider myself lucky.
Today I played and streamed for five hours straight without a hiccup. Except... I noticed that memory usage keeps piling up both in RAM and VRAM, and eventually the game becomes draggy... the fps is there (high, in 80-100s), but looking around gives the feeling that looking around has become a 'heavy' operation. I am with Asus 3090 Strix OC + i7-12700K, also everything maxed out.
Tho, as I explain
here, I'd try to run my RAM faster before I point to something else as the problem. At that point, CP2077 had some 11-12 GB allocated, and that's quite a bit of data to move around.