Are you on PC? What's your hardware? It's always good to add that information.
Did you try lowering the settings to see if that has anything to do with it?
If you are on PC, did you try to verify/repair the game as explained here:
Welcome to CD PROJEKT RED Technical Support! Here you will find help regarding our games and services, as well as answers to frequently asked questions.
support.cdprojektred.com
Here's some more information regarding crashes from CDPR support:
Welcome to CD PROJEKT RED Technical Support! Here you will find help regarding our games and services, as well as answers to frequently asked questions.
support.cdprojektred.com
(to contact CDPR support, please click on "Contact Us")