There should also be kids and youth who smoke.
Much as that would make sense within the context of the world, it would be a nearly impossible sell to the wider market. The game would be banned outright in many places, and I can't even begin to think of what that would cost CDPR as a result. It might be a "bold statement"...but very often that level of radical disregard for societal values is often sacrificed in the process of making its point. (Granted, we see such things in films all the time, but video games are still widely regarded as a medium put into children's hands and interactive, which will automatically make it degrees of magnitude worse in people's minds. Mostly, people who don't play or understand video games. But the public reaction would still be just as vicious.)