I'd like to clarify something too. I'm not opposed to stories where romance is at the center of it. They have a place in video games. Fixed romances can work in games where the protagonist is also fixed. I simply think that a game like Cyberpunk with a semi-fixed protagonist like V isn't the right kind of game for something like this.I wouldn't say that was a "problem" unless you consider every single game, movie, book, etc. to be problematic for not catering to every single person on the planet. You're never going to make everyone happy. Games like this are not heaven-machines. The type of question you're asking could be applied to SO many fixed things. What about the people who don't care to have a relationship with Johnny Silverhand? You can't avoid that in Cyberpunk. What about people who don't want to play a male character who practically has a daughter? You can't avoid that in Witcher 3. What about people who don't want to play a sci-fi? What about the people who don't want to play a fantasy? Etc., etc., etc. All of those are going to be "problems" for someone here or someone there.
Relationship with Johnny is fixed, yes, but you have an ability to decide just what kind of relationship V can have with him. They can be friends, or V can antagonize him repeatedly and refuse to give him control.
The best thing about Cyberpunk's LIs is that they're all different people. They come from different walks of life, they have different goals, different tastes. All this makes them feel more alive and interesting to interact with. One-size-fits-all kind of romance option removes that. At their core, they'd be the exact same character regardless of which gender or sexuality you'd pick for them.