Here I go again:
While exploring one of the less than acceptable areas of the city, you find (or if your street cred is high enough, you're contacted by) a Real Estate Developer.
They're in a bit of a pinch if you find them and you have to rescue them from some thugs. If you've been contacted, then, you find them in the same chancy situation when you go to meet, and must save their bacon.
Down to business - The Real Estate Developer has designs on cleaning up the neighborhood, remodeling ... the usual slum lord song and dance of running out the "riff-raff" to make way for shiny happy people with lots of money to fill the developer's pockets.
Take the job, or not; your decision. If you do, you're given a series of shady business, less-than satisfying quests to clean out buildings, eliminate gangs, squatters, vagrants, hobo camps etc.
After each building, remodeling and construction can begin, and if you show up at one of the locations you cleaned out, there's work crews busy at work, remodeling, rebuilding (Progress on buildings happens over time as you go back to visit on occasion, or, is completed after some arbitrary X in-game time) ... but, sometimes there's trouble. You're called to deal with that trouble, and you recommend hiring some cheap security, so, each job site then also gets a small security detail to protect the workers.
Some of the sites you're told to clean out present the old questions concerning the morality of your actions ... and, if you don't do it, someone else WILL ... or do you go back and kill the Real Estate developer(?) ... but, they're just a cog too, and someone will replace them ... so, how does one deal with this mess?
Are you a good errand boy/girl and clean out all the locations?
One of the sites might contain an old forgotten secret location; a bunker, a misfit luddite community, something of interest that presents a story challenge.
How do you work through this series of jobs?
Do you find another other scumbag Real Estate Developer to Yojimbo back and forth between your original client until both are ruined? What do you do?
Quest chain reward could be a new fancy apartment, possibly leveraged through blackmail regarding all the dirty deeds that were done to get the place built. ... or any number of other things like new contacts, as well as the street cred, and usual coin for doing errands.