My first (150 hour) playthrough was as a Netrunner and towards the end, I kind of just transitioned into a reflexes/blades build.
Overall, I much prefer the gameplay loop of using movement tech to navigate the topography of the environment to close in on enemies. Part of this is because Night City is such an interesting place to do this in. Theres an element of route planning, there is the movement tech execution. I found you can be really creative with it.
This is a clip of a farming loop I settled into when I decided I didn't want to netrun anymore and needed the perks to transition into blades:
Even something as rigidly farmable as hitting up Pacifica set spawn locations ends up having a lot of creativity and improvisation with air dodging so that every loop isn't the same. Just like playing Genji in Overwatch, you think about your environment differently when you have more options to traverse it.
And thats why I found netrunning so ultimately unsatisfying at the end. Its the same every single time. Legendary ping. Breach. Contagion. Everything dies and you walk into an empty building to collect loot.
I found that the most interesting things in the game for emergent gameplay possibilities were cyberware and perks that enable you to do something you can't do otherwise. For example, the body perk that allows you to reload and shoot while sprinting/vaulting is a big quality of life improvement for gunplay. Double jump cyberware opens up the verticality of every place you visit in the game. Maneuvering Systems cyberware lets you traverse great distances and route plan an assault that wasn't possible before.
On my second playthrough I've decided I want to go 11 body, 20 reflexes, 16 intelligence, 3 technical ability, 20 cool.
11 Body for the athletics perks that enable shooting/reloading while sprinting, sliding and vaulting so gunplay is smoother.
20 Reflexes so I can go full blades/pistols. I can shoot while dodging and dodge while aiming, again making gunplay smoother. Not going rifles/SMGs because the perks mostly require you to be behind cover and I just don't enjoy cover shooter gameplay for how passive/conservative it is. High reflexes also allows you to use cyberware like Maneuvering Systems, Kereznikov etc. which opens up a lot of movement tech.
20 Cool because Cold Blood is just nuts for everything (whether you go melee, guns, hacks).
3 Technical Ability because I really tried to get into crafting but it makes me do so many things that annoy me, I just decided to not partake until the entire system gets an overhaul. I already dislike save scumming to get mod slots on legendary clothing. I really didn't want to do more of it to not get crappy crafts. I really disliked manually deconstructing tonnes of items into components, one at a time.
16 Intelligence because it still allows you to run an effective contagion/ultimate hack builds with Netdriver/Rippler. I want to use a Cyberdeck anyway, not a Berserk or Sandevistan because Legendary Short Circuit applies its damage on crit to all weapons making blades, guns and fists good. In general legendary quickhack passives offer crazy utility like Reboot Optics so you have an option to run into buildings and get out undetected for when you need to do that.