Drivers...OS updates...changes to the APIs...lots of stuff.
In general, anytime we make any sort of change to a system config that's working, we introduce the potential for new issues. Unless there's a specific reason to change or update something, I leave everything exactly the same. I'm still using Windows 7 x64 and Nvidia Reference Drivers 385.69. Everything works just fine. I get excellent performance in both recent or legacy titles.
So, if the issue started now, and the steps above have no effect, try rolling things like drivers
back. Games are built for the hardware and software that were around at that point. New hardware and software will not always be backwards-compatible. (Nor are they supported.) Newer and faster are definitely not always better. The real goal is to try to get your system as close as possible to the operating environment that an older game wants -- and that often means reigning in newer hardware instead of trying to take advantage of it.
As I mentioned in the first response, you're not the first person I've seen that has had this type of stutter with Ryzen chips.
I'm sorry I've got no definitive answer for you there. It simply seems to be a quirk between the game and the processor.