I agree on the "personal storyline" part, but I do disagree on the motive. It sounds a tad generic to have an every saturday revenge or save your family storyline.
I'd rather it was something bit harder to grasp. Mike Pondsmith said Cyberpunk is about saving yourself, and that's a very ripe ground to explore a basic human condition and aspiration in the given world that might lead to a lot of different places. What would it mean to "save yourself" to any one individual and where such might lead him or her. A more of a psychological journey than a specifically concrete one. Such where you start the game and wonder where it might lead you this time around.
Of course it needs to feel motivating and relevant to the character (and the player) so that it isn't just a glorified side quest with a "credits roll" feature at the end. Have a clear beginning and a set of nuanced and strong endings where the player might or might not wind up in and have a closure based on how he's played the game and tackled its dilemmas.
Hellishly difficult to produce and script in such a way that it still feels clear enough and meaningful, no doubt, but that's a place where CDPR can put their money where their mouths are.
