Hello there:
I bought the witcher 2 via steam. I got two Sapphire HD 7970. I run the game with no problems in ultra settings. If I try to run the game with my cards overclocked (no matter if a little overclock speed), the game freeze and crash my PC. I think is a driver problem with in the game, cause I run other games overclocked with great results; but the game runs great at stock clock speeds.