2,4, 6 and 9 mainly due to my pessimism.
4: I'm afraid companions won't get orders properly adding a lot of frustration during gameplay. Imagine being during a complex fight and trying to tell jackie to do something (without pausing the game, everything is in real time in the game and I love it) and the idiot AI doesn't get it and does something else, and he dies. Goddamn. Reload because programmers failed? No thanks, I've seen it too many times. Imagine ellie in TLOU being vulnerable or possible to be seen by unactivated foes, it would have been one of the most frustrating games in history.
9: as I just wrote, stupid AI not covering and getting killed. Or bugs, jackie falling from a certain height and dying becasue stupid or bugged falling damage. If I kill someone because I decide to (directly or indirectly, e.g. I take a decision and the long-term outcome is jackie being dead), absolutely fine, actually I want this. If it's an escort mission, I can accept it, but if the AI dies because it's stupid, I can't bear it.
6: why not? Actually it'd be nice if for once an NPC hits on you and you decide if you're gonna pound that ass or not. It's always the other way round in games, not that realistic