NPC pop-in has become unbearable. NPC's appearing right in front of Geralt, or completely disappearing. NPC's disappear from cutscenes and conversations. Enemy NPC's appear out of nowhere, in combat mode, and immediately attack, often times resulting in death of Geralt. Texture pop-ins have become increasingly worse, be it NPC's with missing hair, only for it to magically appear the closer you get, or clothing doing the same thing. NPC's from cutscenes having the same effect.
Geralt in conversations loses detail on his face, as does Triss, and various characters. LOD is completely broken. Shadows vanish the closer you move towards them, or fill in detail from 2 feet away from Geralt.
Sound cuts off, mainly music while adventuring, in combat or playing GWENT.
Using IGNI often times sets enemies aflame several meters away from Geralt. Two-Handed weapon enemies have no parry animation when you attack more than once, often resulting in Geralt just becoming dazed.
Shadow detail has become increasingly worse, at any setting, and the distance at which shadows render is insanely short, as in the ring around Geralt for foliage and debris.