Contrary to TW3, this time we'll have on-screen signs of where we need to go, therefore I think we'll be able to play without neither minimap or screen, which is very good. So I'll probably disable whatever devs has put in the gme and leave that sign.
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But, if I need to choose, compass for me, but a compass done right. Minimap 99% is "follow those damn dots, CJ!" which I hate, since it distracts me and doesn't make me enjoy (and live!) the world built by devs. I played RDR2 with minimap off and it was great to open the map, check where I needed to go (IE go to that mountain, follow the river north and you'll get to that city) and get help from sign posts (written in english), but during missions it was almost mandatory. Sometimes NPCs gave you advices where to go, but it was not very efficient.
Regarding driving, I keep saying that we need something like this: