I kinda get where your comming from but theres a diffrence to imortality and giving up your life for nothing. Does V prevent Saburo in any way whatever edning you choose? Does it solve anything? A meaningfull death is kinda prefereble in a game. I wanna escape the boring reality. And its not really a choise. its made for you. If you skip the side quests cuz the game pretty much tell you too (hurry your dying) and then get to the end how menny choises do you have in what to do? 2? Is that the replayebility they keept talking about? You have to get to the end and be sad about how it ends so you do all sidequests next time and try again but the end isent much better.But his romantic interest is going to die soon. It's also heavily ambiguous at the end of the first movie as to whether or not he is also a replicant, and therefore destined to die soon as well.
Only in 2049 (a movie that came out 35 years later and does kill the protagonist) that we get an answer as to whether Dekker was a replicant or not.
I love that they don't give us the easy out. The whole story is a very cynical take on why and how certain people have power and also a very cynical take on transhumanism. The original sin in the main plot is Saburo Arasaka wanting to essentially become immortal. That idea of "beating" death is literally his impulse the game is (in part) critiquing. The idea that when we try to play God and transcend mortality, it all goes awry. I think it's unlikely to be a coincidence that the one ending where V tries to survive at all cost by trusting Arasaka is - I think - by and large considered a less favorable ending for V. Acceptance of mortality is a healthy thing, even in video games. No matter what V does, her body can't live forever.
Making the player deal with that and still choose how to proceed knowing death (in some shape or form) is coming soon - that's very interesting to me. Not something that video games do a lot. Her death doesn't make the things V has done any less impactful. The protagonist doesn't have to survive for there to be meaning in the things they did and the story that's been told.
Maybe they'll add in something in an expansion that impacts the ending. I kinda doubt it though. I think the story loses it's teeth a bit thematically that way.