Sadly, in this sound bite world, I haven't made the time to read ALL the previous posts, so at risk of repeating ideas; ......
I would like you to address the tech side of game mechanics. It's a given that you need a concise, precise & fluid combat system (check 'Remember Me' as one example). As I feel that CDPR's forte is story telling & immersion, can we address interruptions. Can we lose loading screens & just have the game go into slow mo or somesuch. Also, can we lose the E sign. I mean, either SUBTLY highlight stuff/people we can interact with, or, even better, give us a type of Witcher Sense, whereby WE use a key to highlight interactables when we choose/need to. Oh, & please, have our character either 'frisk' bodies for loot, or at least reach out a hand!
Inventory. Please, please, please, keep it to a minimal. I don't mean restrict our capacities (ala Res Evil 5 etc) but make a lot of stuff auto, such as food, energy, stamina, whatever & etc. Yes, we have to find it & pick it up, but after that, don't make us have to organise & select such basics please. Keep the inventory for important stuff like weapons, skills, upgrades etc. My biggest bugbear with RPG's in general, is I dread managing the inventory! With some games, I have to allot an hour sometimes to just sorting, benefiting from & tidying up the God damned inventory!
On the loot front, depending on how much, weight limits, Lvl dependency etc. Either give us separate storage banks, or, allow us to mark stuff of interest, to pick up later (assuming 'open world') Finally, dying. Is there any way to mesh this into the game? An exemplar is 'Prey', where, on dying, you went to the spirit world for a short period before being reborn back into the game! Borderland's 'new you' & Bioshock's 'vita-chamber' are acceptable, but not very inventive imho. Maybe we could lose gear on dying too, & have to retrieve it from that gang/enemy (bosses excepted) with just fists/knife/pistol ? To make it a bit more important NOT to die!
I know it's tricky, & my exemplar was story specific, but that's why I put it here, gives a chance to consider building it into the story. I'm confident in CDPR's expertise in game design & expect another cracker in Cyberpunk 2077, & now that W3 is out, given support time for that & a well earned holiday break, it will all too soon be time to really concentrate on CP 2077, before they have to change the title date!