I don't think any serious combat shooters use these, not one. Weight, recoil, muzzle flash, simple space...yeah. The reason you carry a pistol is convenience - otherwise, get an actual weapon.
Edit: apologies, of course, to Elmer Keith. There are exceptions. Otherwise, .357 is as high as most people ever need to go. Unless you're hunting Garou.
A guy wearing METALGEAR and skinweave are modern werewolf, u need to pack very heavy caliber weapons to hurt them, not mentioning cyberpsycho FBC moderator called Sardukhar : Don't trust his words, this machine only want to destroy humanity, get your .454 Cassul handgun near you !