After Cyberpunk 2077, I would like to see some other famous franchise to become a game by the hands of CDPR, like Forgotten Realms, Lord of The Rings. Something like Baldur's Gate did, but envisioned by CDPR, and with some heavy dark visuals, like BG2.
If this is not possible, maybe a 1984 (George Orwell) adaptation would be nice, or another distopy without technology.
Another thing that I really was hoping for is to see CDPR developing a Vampire - The Masquerade game (but probably that'll never happen unfortunately), because they said they were fans from the original game.
And, IMO, the masterpiece of japanese cyberpunk, Gunm (known as Alita Battle Angel), but without Hollywood's distortions (which killed the philosophical part of the history).