To be honest I don't experience many, if any technical issues with the game, it runs smoothly for me on my PC (60 FPS) and I have yet to run into a quest in my NG+ play-through that isn't working. Because of this my expectations are this:
1. The Triss romance fix, I prefer Triss over Yen/Shani and have been waiting for this for a long time, i'm putting all my hope and trust in CDPR.
2. I expect them to fix PS4 performance, while I am not a huge fan of consoles, one could even say I hate them, the bugs I have been hearing about are not okay, and we should expect the game to at the very least function on all platforms, so I hope for all you PS4 owners that this fixes it. Once, and for all.
What do I personally want out of the patch? Increased difficulty on NG+, dear god i've been breezing through it so easily on Death March its not even funny. Though i'll hold out until someone makes a mod for this, there must be someone as masochistic as me out there with modding skills.